The brain will entrain to the strongest stimulus. If you combine binaural beats with isochronic tones, your brainwaves will entrain to the isochronic tones. If anything, when you combine the two I believe it makes the track less effective because it makes it harder for the brain to decipher between the two and synchronise to a single beat. There are lots of websites with compelling marketing about the benefits of combining the two together in some funky way, but I haven’t seen any research or lots of anecdotal feedback even to suggest it’s effective to combine them.
Cvetkovic D, Simpson D, Cosic I (2006). “Influence of sinusoidally modulated visual stimuli at extremely low frequency range on the human EEG activity“. Conference proceedings : … Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference 1: 1311 – 4. doi:10.1109
Today, EEG machines are used for diagnosing epilepsy and sleep disorders, for determining dosages for anesthesia, and measuring the brain activity of people in comas or suffering from brain trauma. EEG machines also continue to play a role in researching and understanding brainwave entrainment and developing new and better methods for delivering the benefits of this form of brainwave modification. 
In addition to potentially boosting sleep-promoting hormones, binaural beats may also reduce our perceptions of pain. A 2017 study found binaural beats used in combination with visual stimulation led to reductions in patients’ perception of acute pain. Other recent research showed binaural beats helped improve pain perception in patients with chronic pain.
When I am using equisync I feel kind of like it is “pushing me” – I guess this is the right way to say it- to achieve better results, which I really like. I fall asleep quickly, and sleep all night and even wake up before my alarm goes off. I feel noticeably calm during the workday- which is very helpful for what I do. I really like the warm feeling (my whole body gets really warm during my equisync meditation sessions) and I feel kind of like Im floating while listening. The soothing rainfall is also very nice.
(Shannahoff-Khalsa, 1991; Webb & Dube, 1981). These naturally occurring shifts may underlie the anecdotal reports of fluctuations in the effectiveness of binaural beats. External factors are also thought to play roles in mediating the effects of binaural beats (Owens & Atwater, 1995). The perception of a binaural beat is, for example, said to be heightened by the addition of white noise to the carrier signal (Oster, 1973), so white noise is often used as background. "Music, relaxation exercises, guided imagery, and verbal suggestion have all been used to enhance the state-changing effects of the binaural beat" (Owens & Atwater, 1995). Other practices such as humming, toning, breathing exercises, autogenic training, and/or biofeedback can also be used to interrupt the homeostasis of resistant subjects (Tart, 1975).
4. Theta State: (4 — 8Hz) We're able to begin meditation. This is the point where the verbal/thinking mind transitions to the meditative/visual mind. We begin to move from the planning mind to a deeper state of awareness (often felt as drowsy), with stronger intuition, more capacity for wholeness and complicated problem solving. The Theta state is associated with visualization.
Both brainwave entrainment and neurofeedback deal with brainwaves, but the similarity stops there. Entrainment pushes your whole brain into a pre-determined state, while neurofeedback teaches you how to move specific parts of your brain on your own. It is the differeence between forcing the brain into a given position, and skills building so you can move it there yourself. 

"Wow! I have been doing this Awakening Kundalini guided meditation every morning for about two weeks now. I am a yoga teacher and I have never experienced energy like this before! Every morning, I feel a surge and abundance of endless vital energy nourish my mind, body, and soul. The sounds, theta waves and guidance are perfectly combined to gently awaken the sleeping serpent confirmed by the exquisite sensations experienced. "  --Katarine
When we are mentally active various groups of neurons will be firing and the EEG will look like a jumble of different waves at different frequencies. When we are in a relaxed state, however, our brains settle into a steady rhythm – when fully awake this is the alpha rhythm, which as a frequency of 8-12 hz and other recognizable features. When drowsy our brainwaves slow to the theta range, 6-7hz, and when in deep sleep into the delta range, 4-5hz.
My name is ******. I’m a systems engineer which have worked on the engineering field for over 20 years. During the last few years I have faced some personal challenges which have put a lot of my abilities to a test. Over a year now I got the “Equisync II” CDs from the EOC Institute, and the results from the very beginning were really amazing. Even as an engineer it was not easy to understand the incredible benefits of this brainwaves therapy when used consistently.

Critics, like Owen Flanagan, PhD, believe that Hanson, and those like him, are overextending the results of current scientific studies.[citation needed] In his book Bodhisattva’s Brain: Buddhism Naturalized, Flanagan presents a more conservative viewpoint of current scientific research and cautions readers against the seemingly exciting results of recent studies.[20] Flanagan does not believe current science supports the idea that positive emotion can be strengthened in the same way that stroke victims can recover use of limbs with use.[20] Flanagan does acknowledge that meditation may be beneficial in some way, but the mechanism of how meditation affects the brain is still clouded.[20] Similarly, Awasthi argues that Meditation is non-specific to the research studies showing clinical efficacy in some cases, though mechanisms remain unclear.[21] Flanagan and Hanson use many of the same scientific studies to attempt to support their differing viewpoint, but both authors identify the need and importance of future studies investigating meditation.

Over the centuries people have discovered that repetitious rhythms such as the beating of a drum at a single tone, or chanting, or other methods for producing a single, repetitious rhythm, have been known to produce certain states of consciousness whether deep relaxation, trance, a state of meditation and so on. The rhythms used basically changed the brainwave state of the person listening as long as that person remains open and receptive to the rhythms.
Earlier evidence out of UCLA suggested that meditating for years thickens the brain (in a good way) and strengthens the connections between brain cells. Now a further report by UCLA researchers suggests yet another benefit. Long-term meditators have larger amounts of gyrification ("folding" of the cortex, which may allow the brain to process information faster) than people who do not meditate. A direct correlation was found between the amount of gyrification and the number of meditation years, possibly providing further proof of the brain's neuroplasticity, or ability to adapt to environmental changes.
Binaural beats is a method where two sound waves of different frequencies are introduced into each ear. These frequencies when processed by the brain cancel each other out, creating a whole new frequency. So if we had a tone of 500 Hz in one ear and a 510 Hz tone in the other, the result would be a 10 Hz tone. So while a 10 Hz tone couldn’t be directly heard, using binaural beats we can create that tone inside our brain.
Alpha Waves are electromagnetic oscillations in the frequency range of 8Ð12 Hz arising from synchronous and coherent (in phase / constructive) electrical activity of thalamic pacemaker cells in humans. They are also called Berger's wave in memory of the founder of EEG. They place the brain in states of relaxation times, non-arousal, meditation, hypnosis
Brainwave entrainment is also known as brainwave synchronization.  According to Wikipedia  brainwave entrainment is “any practice that aims to cause brainwave frequencies to fall into step with a periodic stimulus having a frequency corresponding to the intended brain-state (for example, to induce sleep), usually attempted with the use of specialized software.”
As somewhat of a modern mystic, I have studied altered states of consciousness, but due to my monkey mind, I have only been able to experience them to a very minor degree. I have tried so many methods of meditation to little avail. But I became aware that I would not be able to progress in my spiritual life if I could not achieve at least a modicum of success in meditation.
That all said, we are all different and have our own different limits. So I generally advise that you just be aware of how you are feeling, and if you feel like you are getting a bit fatigued from it, it’s probably time to stop or at least take a break. When listening over long extended periods, I recommend that you keep yourself well-hydrated. Your brain needs a good supply of water to function well, especially if you are studying hard and increasing your brainwave electrical activity.

Joseph Kao, creator of Profound Releasing, Profound Renewal, and Sound Asleep, is a hypnotherapist and a solution-focused therapist with a private practice in Cambridge, UK. Joe was the co-developer of an acclaimed course on conversational hypnosis, and he regularly teaches hypnotherapy and psychotherapy to other therapists. He has also been the head scriptwriter for over 800 professional hypnotherapy recordings. Joe was drawn to the world of philosophy, meditation, and brainwave entrainment technology from an early age, and he’s had a daily meditation practice since 1998.

Electroencephalography (EEG) has been used in many studies as a primary method for evaluating the meditating brain. Electroencephalography uses electrical leads placed all over the scalp to measure the collective electrical activity of the cerebral cortex. Specifically, EEG measures the electric fields of large groups of neurons. EEG has the benefit of excellent temporal resolution and is able to measure aggregate activity of portions or the entire cortex down to the millisecond scale. Unlike other imaging based methods, EEG does not have good spatial resolution and is more appropriately used to evaluate the running spontaneous activity of the cortex. This spontaneous activity is classified into four main classifications based on the frequency of the activity, ranging from low frequency delta waves (< 4 Hz) commonly found during sleep to beta waves (13–30 Hz) associated with an awake and alert brain. In between these two extremes are theta waves (4–8 Hz) and alpha waves (8–12 Hz).

Theta: This brainwave pattern is associated with deep relaxation and with some stages of sleep, including the lighter stages of non-REM (NREM) sleep. REM sleep itself is mostly composed of beta wave and other activity that’s similar to an alert, waking brain. Deep meditation produces theta waves, which are slower and lower frequency (between 5-8 hertz) than Alpha waves. That murky barrier between sleep and wakefulness, when you’re drifting in and out of sleep, and your thoughts feel dreamlike and difficult to remember? That’s a theta-dominant state of consciousness.

Brain trait changes have also been observed in neuroimaging studies, most often employing fMRI. In a meta-analysis of 21 neuroimaging studies, eight brain regions were found to be consistently altered, including areas key to meta-awareness (frontopolar cortex/Brodmann area 10), exteroceptive and interoceptive body awareness (sensory cortex and insular cortex), memory consolidation and reconsolidation (hippocampus), self and emotion regulation (anterior cingulate cortex and orbitofrontal cortex), and intra- and interhemispheric communication (superior longitudinal fasciculus; corpus callosum)[13] These changes were distinguished by density increases in grey matter regions and white matter pathways in the brains of individuals who meditate in comparison to individuals who do not. Of all areas with reported findings, a greater number of structural changes were found in the left hemisphere.
One larger and more recent randomized and controlled trial looked at the use of binaural beats in 291 patients admitted to the emergency department at a hospital. The researchers observed significant decreases in anxiety levels in patients exposed to audio with embedded binaural beats compared to those who listened to audio without binaural beats or no audio at all (headphones only).
Effects on cortisol: The hormone cortisol is commonly associated with stress, and when levels are higher than usual, it can have a negative impact on the body. High levels of cortisol can lead to a range of conditions, including Cushing syndrome, menstrual cycle and female libido changes, anxiety, and depression. Dr. Giampapa noted a reduction of cortisol of up to 70-80 percent in several study participants.